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Disseminated Intravascular Coagulation
Summary
Disseminated intravascular coagulation (DIC) is a syndrome characterised by systemic intravascular activation of coagulation, leading to the widespread deposition of fibrin, with formation of widespread microvascular thrombosis. These microthrombi impair organ perfusion and thus contribute to organ failure. During the coagulation process, consumption of coagulation factors and aggregation of platelets occur resulting in reduced levels of both procoagulant and anticoagulant clotting proteins. Therefore patients with DIC may have both thromboembolic events and hemorrhage.
General Information
Enrolled trainees 1959
Open 06.04.2020
Available for ESICM members
Student effort 3
Last Updated March 15, 2022
Intended Learning Outcomes
At the end of the Unit the student should able to:
- Describe the clinical syndrome of disseminated intravascular coagulation (DIC)
- Understand clinical consequences of DIC including the risk for bleeding and thrombosis
- Describe the pathophysiology of DIC
- Recognize the patient at risk for DIC
- Interprete laboratory findings in DIC
- Determine the likelihood of DIC with the use of scoring systems
- List differential diagnoses of DIC
- Describe supportive care for DIC
- Describe transfusion strategies for DIC
- Describe current and future anticoagulant strategies for DIC
- Understand the prognosis and clinical outcomes of DIC
Relevant competencies in CoBaTrICE
- 2.1 Obtains a history and performs an accurate clinical examination
- 2.2 Undertakes timely and appropriate investigations
- 2.10 Integrates clinical findings with laboratory investigations to form a differential diagnosis
- 3.1 Manages the care of the critically ill patient with specific acute medical conditions
- 4.1 Prescribes drugs and therapies safely
- 5.10 Performs arterial catheterisation
- 6.1 Manages the pre- and post-operative care of the high risk surgical patient
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