Most critical care research is underpinned by a knowledge base of biology, drawn from various scientific disciples including anatomy, physiology, immunology, biochemistry, genetics and microbiology. Scientific work in this area often cuts across a range of disciples and may involve collaborative teams of scientists with complementary skills. Not all critical care researchers will undertake this type of research, however an understanding of this area is important as solid underpinning biological knowledge base is key to identifying likely therapies.

This self-study course is a key component of phase 2 of the ESICM research education pathway and needs to be completed before attending the “nuts and bolts of critical care research design” masterclass. Understanding the concepts contained in this module are key to getting the most out of the masterclass, as the masterclass will extend your knowledge and skills in this area. This is intended as an introduction. For those seeking more detail, hyperlinks to more in-depth resources have been embedded, however these are not essential for the completion of the module.